Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of the dissociation constants for the Tamalin PDZ binding peptides
| Protein | Sequence | Wild-type Kd (μM) | Glu114Lys Kd (μM) |
|---|---|---|---|
| mGluR1 (467.4 RU)a | LRDYKQSSSTL | 135 | 162 |
| mGluR5 (449.8 RU)a | IRDYTQSSSSL | 85.3 | 160 |
| Ser-1Ala/Ser-3Ala (426.8 RU)a | IRDYTQSASAL | 181 | ND |
| Intrinsic Ligand (540.8 RU)a | NRSLEEEESQL | 631 | 74.6 |
| aValues in parentheses indicate the amount of immobilized peptides as response units. ND, not determined. | |||
