. 2007 Mar 22;26(8):2061–2070. doi: 10.1038/sj.emboj.7601655

Table 1.

Comparison of the adaptor properties of MecA and phosphorylated McsB

Adaptor	Interaction with NTD and Li domain of ClpC	Induction of ClpC ATPase	Degradation in the absence of substrate	Substrates targeted to ClpCP degradation	Regulators of adaptor activity	Expression of adaptor regulated by	Process controlled by proteolysis
McsB-P	+^a	+^a	+^a	CtsR^a,h,j	McsA, YwlE^a	Heat shock, oxidative stress, general stress response^f	Heat shock, oxidative stress and general stress response^f
MecA	+^b	+^b,c	+^b,c	ComK, ComS^d,h, Spx^e,i, α-casein^i,j and aggregated protein^c,i	ComS^d	Oxidative stress^g	Competence^d and protein quality^c
^a This work; ^b Kirstein et al (2006); ^c Schlothauer et al (2003); ^d Turgay et al (1998), ^e Nakano et al (2002); ^f Krüger et al (2001); ^g Leichert et al (2003), Nakano et al (2003); ^h in vivo and in vitro; ⁱ in vitro ^j phosphorylated.