FIGURE 2.

Typical alignments of exons to the flanked region of other organisms. In A, a skipped exon of the cdc37l gene provides an example of a well-conserved class of exons showing very good sequence conservation (mismatches underlined) with no insertions and the AG/GT splice signals (bold) are conserved, while in B, a skipped exon of the dnajc7 gene shows an alignment typical of the second class, with conservation similar to the surrounding intron including a large insertion (italic) and splice-sites mutated.