FIGURE 3.
A 3D model of a complex between SmpB, EF-Tu•GTP, and tRNA-like domain (TLD) of tmRNA (green). Nucleotides of TLD protected from lead(II) cleavage are shown in red (G333–C335) and pink (U16, U17). The model was derived by combining the crystal structure of the SmpB•TLD complex (PDB file 1V6P) with a crystal structure of EF-Tu•GTP in complex with Phe-tRNAPhe (PDB file 1TTT) by aligning the T loop of tRNA and TLD.