Skip to main content
. 2007 Feb 8;26(4):1163–1175. doi: 10.1038/sj.emboj.7601568

Figure 4.

Figure 4

AGM and fetal liver CFU-C assays from 11.5 d.p.c. fetuses. (A) Total number of CFU-Cs (erythroid+granulocyte macrophage+granulocyte erythrocyte monocyte megakaryocyte) per AGM region of Runx1m/m fetuses. Error bars represent 95% confidence intervals. All m/m fetuses were significantly different from +/+ (*). P-values were determined by unpaired two-tailed Student's t-test. n+/+=38; nf/f=9; nR174Q/R174Q=4; nR177X/R177X=3; nL148F/L148F=5; nT161A/T161A=5; nT149A/T149A=10. +/+ values are pooled from all m/+ intercrosses. (B) Total number of fetal liver CFU-Cs (11.5 d.p.c.). All m/m values were significantly different from +/+ (*). n+/+=59; nR174Q/R174Q=3; nR177X/R177X=4; nL148F/L148F=5; nT161A/T161A=5; nT149A/T149A=12. (C) Total number of CFU-Cs per AGM region from Runx1m/+ fetuses. Significant differences from ΔE4/+ (*) are indicated. The difference between R174Q/+ and ΔE4/+ was significant at P=0.06 by unpaired two-tailed Student's t-test, and at P=0.03 by unpaired one-tailed Student's t-test. n+/+=38; nΔE4/+=15; nR174Q/+=14; nR177X/+=10; nL148F/+=8; nT161A/+=10; nT149A/+=39. (D) Total number of CFU-Cs per 11.5 d.p.c. Runx1m/+ fetal liver. Significant differences from ΔE4/+ (*) are indicated (unpaired two-tailed Student's t-test). n+/+=59; nΔE4/+=24; nR174Q/+=13; nR177X/++19; nL148F/+=9; nT161A/+=9; nT149A/+=41.