Fig 2.

Hsp70 heterodimer nucleotide and protein-folding cycle. The well-established Hsp70 nucleotide cycle is shown taking into account heterodimerization with an atypical Hsp70 and nucleotide status of both proteins. Characteristics of each step are outlined in the main text. The typical Hsp70 is represented with white boxes and the atypical with grey boxes. A peptide substrate is represented as the black squiggle line associated with the typical Hsp70