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The albino T373K TYR mutation causes retention in the ER. Micrographs showing green fluorescence from the chimeric proteins WT TYR-GFP (WT) and TYR(T373K)-GFP (T373K) (Left), transiently expressed in WT mouse melanocytes, calnexin (CNX), and α-1,2-mannosidase II (Mann) stained with rhodamine (Middle), and merge of the two respective images (Right). (The bars represent 1 μm.)
