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Peripheral blood and liver from Tg.AC mice with erythroleukemia. A: Numerous metarubricytes (closed arrows) and smudge cells (s) are intermingled with erythroblasts (open arrow), including a single cell in mitosis. B: Blood smear immunostained for GATA-1 demonstrates nuclear localization in several erythroblasts. Note that the metarubricytes are unstained (arrow). Magnification, ×2500.
