Table 2.
Comparison of Conventional PCR versus Fluorogenic PCR in the Detection of t(14;18) (q32;q21)
Diagnosis | No. of cases | Conventional PCR | Fluorogenic PCR | ||
---|---|---|---|---|---|
bcl-2 mbr positive | bcl-2 mcr positive | bcl-2 mbr positive | bcl-2 mcr positive | ||
Reactive lymphoid hyperplasia | 2 | 0 | 0 | 0 | 0 |
Other nonneoplastic proliferations | 13 | 0 | 0 | 0 | 0 |
Follicular lymphomas | |||||
Large cell | 8 | 4 | 2 | 4 | 2 |
Mixed cell | 7 | 4 | 1 | 3 | 1 |
Small cleaved cell | 9 | 6 | 1 | 6 | 1 |
Other lymphomas | |||||
Small lymphocytic | 4 | 0 | 0 | 0 | 0 |
Diffuse large cell | 8 | 6 | 1 | 6 | 1 |
Diffuse mixed cell* | 1 | 0 | 0 | 0 | 0 |
Unclassified B cell | 1 | 0 | 0 | 0 | 0 |
*Follicle center cell type.