Table 2.
Expression of p27Kip1, MIB1, and p53 in 50 Cases of MCL
| Diagnosis | No. of cases | p27Kip1 (%) (range) | Ki-67 (%) (range) | p53+ # of cases |
|---|---|---|---|---|
| Typical MCL | ||||
| p27Kip1 negative | 35* | 0 (0–1) | 24 (2–90) | 7 |
| p27Kip1 positive | 5 | 81 (50–95) | 16 (2–31) | 1 |
| Blastic MCL | ||||
| p27Kip1 negative | 2 | 0 (0–0) | 82 (80–83) | 2 |
| p27Kip1 positive | 8 | 72 (30–95)† | 65 (32–100) | 5 |
*Includes all 11 cases of multiple lymphomatous polyposis.
†Most cases showed weak but definite staining for p27Kip1, at an intensity lower than the intermingled T cells.