Table 2.
Summary of the Immunohistochemical staining for Ki-67 in the Normal Colorectal Mucosa, Colorectal Tumors, and Metastases of Colorectal Carcinomas
| n | Mean Ki-67 SF (median, range) | Mean Ki-67 DE (median, range) | Mean Ki-67 SF/DE | |
|---|---|---|---|---|
| Normal epithelium | 16 | 0 (0, 0–0) | 0.9 (1, 0–2) | 0 |
| Hyperplastic polyps | 8 | 0 (0, 0–0) | 2.0 (2, 2–2) | 0 |
| Adenomatous lesions | 39 | 1.7 (2, 1–2) | 0.5 (0, 0–2) | 3.4 |
| SD | 13 | 1.7 (2, 1–2) | 0.2 (0, 0–1) | 8.5 |
| MD | 19 | 1.6 (2, 1–2) | 0.5 (0, 0–2) | 3.2 |
| GD | 8 | 1.9 (2, 1–2) | 1.1 (1,5, 0–2) | 1.7 |
| Malignant lesions | 21 | 1.8 (2, 1–2) | 1.5 (2, 0–2) | 1.2 |
| Grade I | 6 | 2.0 (2, 2–2) | 1.7 (2, 1–2) | 1.2 |
| Grade II | 9 | 1.9 (1.5, 1–2) | 1.7 (1.5, 1–2) | 1.1 |
| Grade III | 6 | 1.4 (1, 0–2) | 1.2 (1, 0–2) | 1.2 |
| Metastases | 7 | 0.6 (1, 0–2) | 0.6 (1, 0–2) | 1.0 |
SF, superficial epithelial staining; DE, deep epithelial staining; SD, slight dysplasia; MD, moderate dysplasia; GD, grave dysplasia.