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. 1998 Aug;153(2):373–379. doi: 10.1016/S0002-9440(10)65581-2

Figure 3.

Figure 3.

REMS-PCR detection of mutant K-ras in DNA from paraffin-embedded tumor tissue. DNA from paraffin-embedded sections of the colorectal tumors analyzed in Figure 2 ▶ are shown (C1 to C6). Control samples (+), (−), and Calu are as for Figure 2 ▶ . Mutant K-ras is present in tumors C1 to C3, whereas tumors C4 and C5 are wild type. Although a weak control amplicon is present in C6, the sample was designated as indeterminate because of insufficient amplification. Also shown is analysis of DNA from two pancreatic tumors (P1 and P2) that contain mutant K-ras. Products are shown on a 5% NuSieve gel stained with ethidium bromide. MW, phiX174/Hinf.