Table 3.
Effect of Tumor Age on REMS-PCR Reliability
| Tumor age | Paraffin | Fresh | ||||
|---|---|---|---|---|---|---|
| Wild type | Mutant | Indeterminate | Wild type | Mutant | Indeterminate | |
| <1 year | 11 | 0 | 0 | 27 | 7 | 0 |
| 1–3 years | 22 | 4 | 2 | 60 | 15 | 0 |
| 3–6 years | 18 | 5 | 1 | 19 | 11 | 0 |
| 6–10 years | 1 | 7 | 3 | NA | NA | NA |
| >10 years | 2 | 0 | 4 | NA | NA | NA |
Results of REMS-PCR analysis are shown for both paraffin-embedded and fresh (frozen) tissue, according to the age of the tumor at the time of analysis. Paraffin sections were from colorectal, pancreas, renal, and breast cancers, whereas fresh tissues are from only colorectal tumors. Numbers represent the number of tumors in each category.
NA, not available.