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Cytokine and chemokine expression in the CNS of GFAP-TNFα mice (GT-2). Total RNA from CNS tissue from control (c), presymptomatic GT-2 (p), or symptomatic (s) GT-2 was analyzed for cytokine (A) and chemokine (B) expression as described in Materials and Methods. Principal areas with altered cytokine and chemokine expression co-localized with transgene expression.
