Figure 3.
Survival of injected melanoma cells as multicellular foci in liver, assessed in thick sections by the cell accounting technique. Only 2% of injected cells had formed micrometastases (4 to 16 cells) by day 3, and most of these had disappeared by day 13. Only 1 in 100 of the micrometastases, representing 0.02% of injected cells, had continued to grow into macroscopic tumors by day 13 (which virtually all form at the liver surface). Error bars represent SD.