Table 2.
Morphological Features of 60 ALK-Positive Lymphomas
Morphological appearance | Number ALK+/tested | Tumor cells; Pattern of ALK positivity |
---|---|---|
Common | 45 /68 | 23/45; all c+ n* |
15/45; many c+ n,† few n‡ | ||
7/45; all c* | ||
Lymphohistiocytic | 6 /6 | 6/6; few c+ n,† many n‡ |
Small cell | 5 /5 | 5/5; few c+ n,† many n‡ |
Giant cell | 2 /6 | 1/2; all c+ n* |
1/2; all c* | ||
Hodgkin’s like | 2 /15 | 1/2; all c+ n* |
1/2; many c+ n,† many n‡ | ||
Total | 60 /100 |
c, cytoplasmic; n, nuclear.
*Only large anaplastic cells (no small tumor cells were observed in these cases).
†Mostly large anaplastic cells.
‡Mostly small tumor cells.