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Northern blot analysis of MT1-MMP and MT2-MMP mRNA in human livers. Total RNAs were extracted from liver biopsies, resolved by electrophoresis onto agarose gels, and blotted onto Hybond N nylon. MTS, hepatic metastasis from colonic adenocarcinomas; NT, nontumorous samples from livers with metastases (with either minimal histopathological changes (NT) or cholestasis (NT-C).
