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. 2007 Apr 20;3(4):e59. doi: 10.1371/journal.pgen.0030059

Figure 2. Conservation of Gene Expression Increases with Conservation of Sequence.

Figure 2

(A) Othologous human and mouse genes were ranked by their dN/dS ratios, as given in the ENSEMBL database, from least conserved at the DNA sequence level (larger dN/dS), to most conserved. For each of the three pair-wise regional comparisons, the correlation coefficient between human and mouse log ratios was determined and plotted for each quartile of genes.

(B) Orthologous genes were ranked by their percent nucleotide identity, as given in the ENSEMBL database, and quartile correlation coefficients were determined and plotted for each quartile of genes. X, caudate or striatum-to-cerebellum; Circle, cortex-to-cerebellum; Square, cortex-to-caudate or striatum.