TABLE A1.

Notation for the generalized genetic network model

Symbol	Description
di	Gene concentrations.
xi	Monomer concentrations.
yi	Dimer concentrations.
mi	mRNA concentrations.
σi	Translation rates.
γp,i	Degradation rates of the monomers.
γm,i	Degradation rates of the mRNA.
pij	Rate at which protein i is degraded by protein j.
	Unoccupied binding site .
Di	Matrix of occupied binding site concentrations for the ith gene.
	The jth, nth element of Di (binding site occupied by protein n).
ni	Number of protein molecules translated per one mRNA.
	Label for the jth binding site of the ith gene.
N	Number of genes.
Mi	Number of binding sites of the ith gene.
κ±i	Dimerization/dissociation rates of the proteins to/from themselves.
αi	Transcription rate of the ith gene.
K±i	Rate matrix for the binding/dissociation of the dimers to the promoter sites.
	The jth, nth element of K±i (binding/dissociation rate of the nth dimer to the jth binding site of the ith gene).
Hi	The ratio κi/κ–i.
	The ratio .