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. 2007 Feb 26;92(10):3513–3523. doi: 10.1529/biophysj.106.090464

FIGURE 5.

FIGURE 5

Families of whole-cell sodium current traces recorded from tsA201 cells expressing (A) NaChBac/D-91C, (B) NaChBac/D-91E, and (C) NaChBac/D-91K. Currents were generated from a holding potential of −140 mV using 500-ms depolarizing steps from −120 to 50 mV in 10-mV increments as indicated in the center of the figure. The current-voltage relationship (I/V), where the maximum Na+ current was plotted versus the applied voltage for each current trace, can be seen in the inset below the corresponding family of current traces. Voltage-dependence of the steady-state activation (G/V) of the NaChBac/WT channel (n = 13) and the three D-91 mutants (D-91C (n = 9), D-91E (n = 4), and D-91K (n = 15)) (D). The value of the data points are expressed as mean ± SE. See Table 1 for V½ and Kv parameters.