Figure 2.

Representative NMR data obtained for V7R. (a) 4D ¹⁵N,¹³C-edited NOE data showing intramolecular and intermolecular NOEs for residues Arg-7 (left) and Leu-8 (right). NOE cross-peaks to the myristate group are not observed because the myristate group is not ¹³C-labeled. (b) ¹³C-edited/¹²C-double-half-filtered NOE data showing unambiguously assigned intermolecular NOEs between unlabeled myristyl group and ¹³C-labeled protein. Solid lines denote ¹H-¹²C breakthrough doublets NOE peaks.