Table 3.
Effects of CDP (1mg/kg) on c-Fos cell counts in behaviorally-experienced mice
Brain region | Vehicle | CDP | p-value |
---|---|---|---|
Cg1 | 34.9±6.7 | 34.5±11.2 | 0.979 |
NaCc | 14.7±3.4 | 21.3±6.6 | 0.417 |
NaCs | 12.4±2.8 | 18.5±5.8 | 0.387 |
LS | 60.9±16.8 | 43.0±7.3 | 0.946 |
MS/VDB | 7.6±2.5 | 8.1±3.4 | 0.955 |
Pir | 60.7±16.2 | 62.1±12.9 | 0.946 |
M2 | 9.7±1.5 | 16.6±4.2 | 0.169 |
LS2 | 10.9±3.3 | 3.4±1.3 | 0.014 |
MPOM | 57.1±13.9 | 45.4±8.6 | 0.471 |
MPA | 36.9±7.8 | 32.6±5.3 | 0.653 |
LPO | 13.0±3.2 | 12.3±2.9 | 0.864 |
BNSTd | 20.7±5.6 | 16.9±6.9 | 0.189 |
BNSTv | 8.9±2.0 | 8.1±3.0 | 0.397 |
LS3 | 24.4±4.3 | 15.3±5.4 | 0.072 |
LSv | 61.1±13.5 | 35.4±9.0 | 0.127 |
Cg 1& 2 | 50.4±11.0 | 53.8±25.1 | 0.463 |
PVA | 279.4±46.3 | 241.0±31.1 | 0.493 |
PVN | 40.5±10.9 | 69.6±22.2 | 0.282 |
AHA | 15.0±3.7 | 10.6±1.8 | 0.284 |
AAV | 14.7±6.5 | 11.8±2.4 | 0.660 |
SON | 10.0±3.5 | 26.9±11.9 | 0.233 |
MeA | 54.7±16.2 | 37.9±9.7 | 0.536 |
CeA | 16.9±1.4 | 11.8±3.7 | 0.242 |
BLA | 8.3±3.0 | 4.0±1.5 | 0.232 |
AHP | 75.1±12.5 | 62.9±11.3 | 0.478 |
LH | 45.3±10.1 | 35.1±9.6 | 0.481 |
VMH | 15.1±4.8 | 9.1±2.4 | 0.265 |
Dg | 20.0±5.8 | 6.9±1.4 | 0.035 |
Ca1 | 3.0±1.6 | 0.8±0.8 | 0.613 |
Ca2 | 6.0±0.6 | 6.4±1.9 | 0.862 |
Ca3 | 13.0±2.5 | 10.4±3.8 | 0.586 |
VTA | 58.6±10.9 | 61.4±10.3 | 0.855 |
DRD | 61.4±6.7 | 60.3±13.5 | 0.942 |
cPAG | 134.6±14.5 | 87.6±12.1 | 0.026 |
LDTg | 17.6±3.8 | 38.0±25.4 | 0.613 |
LC | 68.7±8.6 | 65.9±23.5 | 0.916 |
PB | 49.4±9.2 | 46.6±20.7 | 0.232 |
Mean(±SEM) of raw data.
Bold indicates p<0.05 between vehicle and CDP.
Cg1=Cingulated cortex; NaCc=Nucleus accumbens, core; NaCs=Nucleus accumbens, shell; LS=Lateral septum; MS/VDB=Medial septal nucleus/nucleus of vertical limb of diagonal band; Pir=Piriform cortex; M2=Motor cortex 2; MPOM=Medial preoptic nucleus, medial part; MPA=Medial preoptic area; LPO=Lateral preoptic area; BNSTd=Bed nucleus of stria terminalis, dorsal; BNSTv=Bed nucleus of stria terminalis, ventral; LS3=Lateral septum 3; LSv=Lateral septum, ventral; Cg 1&2=Cingulate cortex 1 & 2; PVA=Paraventricular thalamic nucleus, anterior; PVN=Paraventricular thalamic nucleus; AHA=Anterior hypothalamic area, anterior; AVA=Anteroventral thalamic nucleus; SON=Supraoptic nucleus; MeA=Medial amygdaloid nucleus, anterior part; CeA=Central amygdaloid nucleus; BLA=Basolateral amygdaloid nucleus, anterior part; AHP=Anterior hypothalamic area, posterior part; LH=Lateral hypothalamus; VMH=Ventrolateral hypothalamic nucleus; Dg=Dentate gyrus; Ca1=Field CA1 of hippocampus; Ca2=Field CA2 of hippocampus; Ca3=Field CA3 of hippocampus; VTA=Ventral tegmental area; DRD=Dorsal raphe nucleus; cPAG=Periaqueductal grey, caudal; LDTg=Lateral dorsal tegemental nucleus; LC=Locus coeruleus; PB=Parabrachial nucleus.