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. Author manuscript; available in PMC: 2007 Apr 20.
Published in final edited form as: J Control Release. 2006 Oct 24;117(2):227–237. doi: 10.1016/j.jconrel.2006.10.017

Fig. 5.

Fig. 5

Examples of poor and good microneedle coatings via brightfield micrographs of vitamin B coated microneedles. Poor, non-uniform coatings with base-substrate contamination on: (A) a single microneedle and (B) a 50-microneedle out-of-plane array. Improved coating uniformity and elimination of base-substrate contamination after addition of coating solution excipients and use of a micro-dip-coating device for (C) a single microneedle, (D) a 50-microneedle out-of-plane array, and (E) an in-plane microneedle row. Controlled length segment coverage at (E1) uncoated, (E2) 25% coated, (E3) 50% coated, (E4) 75% coated and (E5)100% coated, demonstrating spatial control of the microneedle coating process.