Table 3.
Mean expression of spleen genes at baseline by treatment group
| Gene bank accession # | Gene description | Gene function | PBS | E-selectin 0.1 | E-selectin 5 | P-value |
|---|---|---|---|---|---|---|
| U02553 | Protein tyrosine phosphatase, nonreceptor type 16 | Induction of chemokine activity (10) | 2.67 | 1.21 | 1.54 | 0.0006 |
| AJ243338 | RT1 class Ib gene | Bind and present peptides to NK and CD8+T cells (11) | 0.81 | 0.91 | 0.64 | 0.0008 |
| AI410860 | Rab geranylgeranyl transferase, a subunit | Regulators of cell vesicular transport (12) | 0.48 | 0.32 | 0.39 | 0.0010 |
| NM_017066 | Pleiotrophin (heparin-binding factor, Hbnf, in the mouse) | Regulates cell growth and proliferation (13) | 0.79 | 0.45 | 0.25 | 0.0016 |
| NM_012745 | CD94 antigen (located within the rat natural killer gene complex) | Regulate immune response by regulating effector functions and cell survival of NK and CD8 T cells (14) | 1.26 | 1.21 | 0.56 | 0.0019 |
| NM_017177 | Choline/ethanolamine kinase | Glycerolipid metabolism | 1.0 | 1.28 | 1.38 | 0.0033 |
| NM_017124 | CD37 antigen | T- to B-cell interaction (15) | 6.13 | 5.26 | 9.04 | 0.0033 |
| AF323608 | Fibrinogen-like 2 | Cytokine inducible, procoagulant (16) | 2.11 | 2.09 | 0.68 | 0.0039 |
| NM_012855 | Janus kinase 3, protein-tyrosine kinase | Cell growth and maintenance, cytokine signaling (17) | 0.57 | 0.88 | 1.17 | 0.0044 |
| M12492 | Protein kinase, cAMP-dependent regulatory, type II beta | Cell proliferation, adhesion, signaling (18) | 0.94 | 1.0 | 0.67 | 0.0046 |
| BM391807 | Nyggf2 protein | Unknown | 1.13 | 1.18 | 0.86 | 0.0046 |