Table 1.
Estrogen Receptor-α and Progesterone Receptor Staining in Ovary and Serous Ovarian Tumors
% labeled nuclei | Normal ovary (10) | Cystadenoma (11) | Borderline tumors (5) | Carcinoma (16) |
---|---|---|---|---|
ERα 0 to 29% | 10 (100%) | 1 (9%) | 1 (20%) | 6 (37.5%) |
30 to 60% | 0 (0%) | 5 (45.5%) | 2 (40%) | 6 (37.5%) |
61 to 100% | 0 (0%) | 5 (45.5%) | 2 (40%) | 4 (25%) |
PgR 0 to 9% | 6 (60%) | 1 (9%) | 0 (0%) | 13 (81%) |
10 to 25% | 0 (0%) | 1 (9%) | 5 (100%) | 3 (19%) |
26 to 100% | 4 (40%) | 9 (82%) | 0 (0%) | 0 (0%) |
Legend: The percentage of positive nuclei for ERα and PgR staining was determined as described in Materials and Methods and Figure 7 ▶ . Only 10 of the 16 normal ovaries analyzed for fibulin-1 were analyzed for ER and PgR, as surface epithelial cells were detached by fixation in 6 of them.