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Mitochondrial Enzyme Activity in Normal Donor Heart Samples (n = 6) and in DCM Explanted Hearts from Patients without (n = 12) and with (n = 5) mtDNA Mutations
| Controls | DCM* without mtDNA mutations | DCM with mtDNA mutations | P values | |
|---|---|---|---|---|
| Cytochrome c oxidase | 170.450 | 143.917 | 86.117 | 0.0008 |
| NADH dehydrogenase | 1401.5 | 1475.083 | 1278.600 | 0.0388 |
| Succinic dehydrogenase | 49.217 | 42.730 | 49.750 | NS |
Statistical analysis was performed with the Student’s t-test. NS, not significant.
