Table 3.
Univariate Analysis of p27 Expression and Prognostic Factors
| Variable | p27 | P value | |
|---|---|---|---|
| High expressors | Low expressors | ||
| Age (years) | |||
| ≤55 | 14 (54%) | 12 (44%) | NS |
| >55 | 12 (46%) | 15 (56%) | |
| Race | |||
| Caucasian | 23 (89%) | 24 (89%) | NS |
| Other | 3 (12%) | 3 (11%) | |
| Tumor stage | |||
| IIC | 4 (15%) | 3 (11%) | NS |
| III | 22 (85%) | 24 (89%) | |
| Residual disease | |||
| Microscopic | 10 (42%) | 6 (38%) | 0.02 |
| <2 cm | 9 (38%) | 5 (19%) | |
| >2 cm | 5 (21%) | 15 (58%) | |
| Performance status | |||
| 0 | 10 (39%) | 4 (15%) | 0.02 |
| 1 | 16 (62%) | 20 (74%) | |
| 2 | 0 | 3 (11%) | |
| Differentiation | |||
| Well/moderate | 11 (42%) | 8 (30%) | NS |
| Poor | 15 (58%) | 19 (70%) | |
| p53 expression | |||
| Negative | 11 (44%) | 9 (33%) | NS |
| Positive | 14 (56%) | 18 (67%) |
NS, not significant.