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. 2007 Apr 10;7:31. doi: 10.1186/1471-213X-7-31

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Copyright © 2007 Pritchett et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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SDF-1 promotes axon elongation and branching in cortical neurons. (a-f) Representative reconstructions of GFP labeled neurons in SDF-1 treated (a-c) and control (d, e) cultures; note the elongated and branched axons in SDF-1 treatment compared to shorter axons in controls (arrows). (f) Graph illustrates the average length of GFP+ axons in control and treated cultures. (g) Stacked graph shows the frequency of branching in control and treated cultures. Scale bar: 90 μm. ****: Significance at p < 0.0001 (chi-square test).