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Airway responsiveness to MCh after sensitization with OVA and challenge with either OVA or PBS in IL-10-deficient (IL-10−/−) and WT mice. Airway responsiveness was monitored by measuring RL (A) and Cdyn (B) as described in Methods. The results for each group are expressed as means ± SEM. Data represent two comparable experiments with 10 mice per group. *, Significant differences between the groups (ANOVA and Tukey-Kramer, P < 0.05). BL, baseline; SAL, saline.
