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Dual-fluorescent immunostaining of ABCG2 and CK19 in normal liver, dysplastic nodule, and HCC. In normal liver, bile ducts coexpressed ABCG2 (green) and CK19 (red). Coexpression of ABCG2 and CK19 is commonly observed in periportal hepatocytes in dysplastic nodule (center of the field is an intranodular portal tract) and scattered cancer cells in HCC (arrows). Original magnifications: ×400 (normal liver, HCC); ×200 (dysplastic nodule).
