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. 2000 May 16;97(11):6019–6024. doi: 10.1073/pnas.100391597

Figure 1.

Figure 1

Characterization of Thor sequences. (A) Restriction map of the genomic DNA surrounding the Thor P-element insertion (P-lacW) at polytene chromosome position 23F–24A. Arrangement of transcribed region and placement of insertion between the TATA box sequence and start codon also is indicated. Restriction enzyme abbreviations: G (BglII), P (PstI), H (HindIII), B (BamHI), and E (EcoRI). (B) Nucleotide sequence (top row) and predicted amino acid sequence (bottom row) of THOR. The start and stop codons are shown in bold with the intron represented by a dashed line. The predicted PolyA signal sequence is underlined. GenBank accession no. AF244353. (C) Amino acid alignment of THOR to 4E-BP sequences. Additional GenBank accession nos. are for human 4E-BP: h4E-BP1 (NM004095), h4E-BP2 (NM004096), and h4E-BP3 (NM003732); for mouse PHAS-I (U28656.1) and PHAS-II (U75530); for zebrafish: zf4E-BP3 (AI722723); Dictyostelium discoideum (C94507); and Schistosoma mansoni (AI014205).