TABLE 1.

Estimation of K_e and S_e for 20 vertebrate proteins

Genes	dN/dS (H–M)	H	Ke	Se
Adiponectin receptor protein 2	0.109	0.785	2.30	−12.32
GTP cyclohydrolase I	0.188	0.586	2.68	−7.16
F-box protein 34	0.274	0.355	2.90	−5.39
RNA methyltransferase-like 1	0.221	0.422	3.26	−6.18
Galectin-3	0.148	0.393	4.79	−7.63
Glia maturation factor (GMF)β	0.047	0.729	5.97	−11.65
Metalloprotease 1	0.076	0.514	6.31	−9.94
Nucleolar GTP-binding protein 1	0.049	0.650	6.64	−11.34
Sperm tail protein SHIPPO1	0.063	0.286	8.18	−10.80
Transaldolase	0.042	0.524	8.23	−11.96
CGTHBA protein	0.030	0.654	8.23	−12.93
Rhomboid family 1	0.024	0.582	9.64	−13.77
Nucleoredoxin	0.020	0.641	9.80	−14.38
Myosin lc (Myosin Iβ)	0.023	0.573	9.85	−13.93
Exocyst complex component 5	0.023	0.566	9.94	−13.97
Plakophilin-3	0.034	0.343	9.97	−12.89
Homeobox protein OTX2	0.014	0.360	12.74	−15.83
Cornichon homolog (TGAM77)	0.001	0.886	15.83	−23.63
14-3-3 protein epsilon (14-3-3E)	0.001	0.777	17.77	−23.61
F-box/LRR-repeat protein 14	0.001	0.507	20.40	−24.27

The d_N/d_S ratio was calculated from the human (H) and mouse (M) orthologous genes.