Figure 2. ICAM-1 governs VEGF mediated eNOS activity.
Panel A shows is a western blot comparing eNOS phosphorylation at Ser1177 in response to 50 ng/mL VEGF164 in WT and ICAM-1−/− MAEC over 30 min. Panel B illustrates DAF-FM fluorescence in response to VEGF164 in WT and ICAM-1−/− MAEC over 1 hour. Closed squares indicate WT MAEC, closed circles indicate WT MAEC + 50 ng/mL VEGF164, open squares indicate ICAM-1−/− MAEC, and open circles indicate ICAM-1−/− MAEC + 50 ng/mL VEGF164.