Table 2.

Microarray Detection of Genes Changing Expression with H₂O₂ Treatment CMCs or HFs were treated with 100 μM H₂O₂ for 1 hour and were placed in fresh culture medium for 24 hrs recovery before harvesting RNA for Affymetrix Gene Array Analyses (see Methods). The data indicates the averages and standard deviations of fold changes from 4 comparisons. The fold of increase or decrease (negative numbers in italic) for each comparison was determined by Microarray Suite 5.0.1 as statistically significant changes. The column in the table represents 1) Affymetrix sequence number, 2) UniGene number, 3) common name of the genes, 4) fold of changes in CMCs and 5) fold of changes in HFs.

Antioxidant/detoxification enzymes			CMCs	HFs
1387599a	Rn.11234	NAD(P)H dehydrogenase, quinone 1	3.11±0.48	4.14±1.90
1370902	Rn.23676	aldose reductase-like protein	3.06±0.52	4.02±1.26
1387669a	Rn.3603	epoxide hydrolase 1	2.47±0.25	2.50±0.51
1372599	Rn.7854	microsomal glutathione S-transferase 2	2.31±0.26	2.26±0.68
1367612	Rn.2580	microsomal glutathione S-transferase 1	1.72±0.18	2.73±0.81
1388122	Rn.44821	glutathione S-transferase, pi 2	1.81±0.25	1.97±0.20
1369940	Rn.3136	transaldolase 1	1.99±0.36	2.31±0.26
1370678s	Rn.102240	monoamine oxidase A gene	1.92±0.35	1.60±0.05
1368990	Rn.10125	cytochrome P450 1B 1 (Cyp1b1)	1.84±0.22	1.60±0.10
1370080	Rn.3160	Heme oxygenase	2.22±0.49
1387759s	Rn.26489	UDP glycosyltransferase 1 family, A6		2.66±0.88
1370613s	Rn.64664	UDP glycosyltransferase 1 family, A7		2.21±0.40
1369926	Rn.1491	glutathione peroxidase 3		1.87±0.13
1367774	Rn.10460	glutathione S-transferase, α 1		1.81±0.16
1372297	Rn.15990	glutathione S-transferase 8(GST class α)		1.64±0.31
1367995	Rn.3001	catalase		1.58±0.19
1370172	Rn.10488	superoxide dismutase 2		1.49±0.10
1386958	Rn.67581	thioredoxin reductase 1		1.50±0.26
1367870	Rn.3578	thioredoxin-like 2		1.38±0.05
1367613	Rn.2845	peroxiredoxin 1		1.36±0.15
1388300	Rn.1916	microsomal glutathione S-transferase 3	−2.92±1.13
1370708a	Rn.10021	3-α-hydroxysteroid dehydrogenase	−1.90±0.43
1367979s	Rn.107152	cytochrome P450, subfamily 51	−1.47±0.13
1387891	Rn.17958	peroxiredoxin 4	−1.36±0.15
Metal binding proteins
1368420	Rn.32777	ceruloplasmin		1.99±0.73
1367565a	Rn.54447	ferritin, heavy polypeptide 1		1.38±0.11
1367559	Rn.1905	ferritin light chain 1		1.32±0.11
1370282	Rn.94754	cysteine rich protein 2		−1.76±0.33
Metabolic enzymes
1386953	Rn.888	hydroxysteroid 11-β dehydrogenase 1	2.38±0.78	3.37±1.58
1370154	Rn.2283	lysozyme	1.73±0.36
1367856	Rn.11040	glucose-6-phosphate dehydrogenase		1.92±0.28
1367982	Rn.97126	aminolevulinic acid synthase 1		1.80±0.34
1387022	Rn.6132	aldehyde dehydrogenase family 1, A1		1.75±0.47
1368976	Rn.11414	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen		1.72±0.29
1386859	Rn.5950	transketolase		1.55±0.22
1372523	Rn.8365	glutamate-cysteine ligase catalytic subunit		1.46±0.24
1371521	Rn.11126	pyruvate dehydrogenase E1 α-like		1.39±0.14
1369931	Rn.1556	pyruvate kinase, muscle		1.39±0.14
1367734	Rn.107801	aldehyde reductase 1 (low Km aldose reductase)		1.39±0.14
1367739	Rn.10325	Cytochrome c oxidase subunit VIII-H (heart/muscle)	−4.71±3.19
1367782	Rn.5119	cytochrome c oxidase, subunit VIa, polypeptide 2	−2.97±1.37
1367626	Rn.10756	creatine kinase, muscle	−2.44±0.96
1369629	Rn.3329	adenosine kinase	−1.84±0.31
1387773	Rn.2202	cytochrome c, somatic	−1.52±0.33
1370276	Rn.1817	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	−1.53±0.21
1370278	Rn.3879	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	−1.49±0.22
1370284	Rn.3454	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit	−1.45±0.21
1370230	Rn.5790	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6	−1.42±0.13
1371335	Rn.107458	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g	−1.42±0.20
1389964	Rn.1318	NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) acyl carrier chain, mitochondrial	−1.53±0.21
1371041	Rn.11092	24-kDa subunit of mitochondrial NADH dehydrogenase	−1.45±0.16
1389012	Rn.18013	NADH dehydrogenase (ubiquinone) 1 β subcomplex, 2	−1.46±0.24
1389288	Rn.14785	NADH dehydrogenase (ubiquinone) 1 α subcomplex, 2 (8kD, B8)	−1.42±0.20
1371381	Rn.35208	Ubiquinol-cytochrome C reductase complex 7.2 kDa protein (HSPC119)	−1.46±0.20
1375197	Rn.3254	Ubiquinol-cytochrome C reductase complex 6.4 kDa protein (Complex III subunit XI)	−1.38±0.11
1370218	Rn.1785	lactate dehydrogenase B	−1.83±0.54
1370939	Rn.6215	fatty acid Coenzyme A ligase, long chain 2	−1.80±0.54
1367857	Rn.28161	fatty acid desaturase 1	−1.69±0.23
1386965	Rn.3834	Lipoprotein lipase	−1.58±0.11
1367707	Rn.9486	fatty acid synthase	−1.45±0.17
1388348	Rn.4243	fatty acid elongase 1	−1.29 ± 0.05
1370355	Rn.1023	stearoyl-Coenzyme A desaturase 1	−1.78±0.25
1367668a	Rn.83595	stearoyl-Coenzyme A desaturase 2	−1.76±0.25
1370191	Rn.6290	ornithine decarboxylase antizyme inhibitor	−1.78±0.42
1367667	Rn.2622	farensyl diphosphate synthase	−1.78±0.16
1387271	Rn.7279	phytanoyl-CoA hydroxylase	−1.73±0.63
1372462	Rn.106162	acetyl-CoA C-acetyltransferase, cytosolic	−1.71±0.37
1370235	Rn.3285	diazepam binding inhibitor	−1.67±0.18
1388403	Rn.3490	Isocitrate dehydrogenase, cytoplasmic (Oxalosuccinate decarboxylase)	−1.65±0.33
1368878	Rn.10780	isopentenyl-diphosphate delta isomerase	−1.59±0.26
1367932	Rn.5106	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	−1.42±0.14
1389908	Rn.73738	β-galactosidase (Lactase)	−1.42±0.10
1372665	Rn.100813	Phosphoserine aminotransferase 1		−1.32±0.09
Endocrine factors, cytokines and binding factors
1367973	Rn.4772	small inducible cytokine A2	3.85±2.70	1.84±1.07
1370770s	Rn.44216	Kit ligand, stem cell factor	2.26±0.68	1.88±0.26
1368238	Rn.9727	pancreatitis-associated protein	4.23±2.16
1386879	Rn.764	lectin, galactose binding, soluble 3	3.22±1.24
1371210s	Rn.39743	MHC nonclassical class I antigen	2.88±0.68
1390507	Rn.16103	interferon stimulated gene (20kD)	1.99±0.36
1373882	Rn.4256	VEGF-D	1.74±0.13
1370082	Rn.40136	TGF β1	1.60±0.24
1387450	Rn.9952	TGF α		1.93±0.62
1387316	Rn.10907	gro		4.33±1.37
1387029	Rn.101777	complement component factor H		4.13±2.42
1388255x	Rn.39743	MHC nonclassical class I antigen, soluble precursor (RT1 class Ib gene)		3.33±0.92
1367850	Rn.6050	Fc receptor, IgG, low affinity III		3.28±1.81
1370154	Rn.2283	Lysozyme		3.05±1.35
1387687	Rn.16316	immunoglobulin superfamily, member 6		2.81±1.03
1368490	Rn.42942	CD14 antigen		1.56±0.22
1368044	Rn.45602	secretogranin 2	−3.87±2.38	−2.73±1.15
1371500	Rn.7961	latent TGF β binding protein 1	−1.83±0.15
1387232	Rn.10318	bone morphogenetic protein 4	−1.42±0.11
1376425	Rn.24539	TGF β2	−1.32±0.07
1371500	Rn.7961	latent TGF β binding protein 4 homologue (46%)		−1.72±0.29
1368448	Rn.40921	latent TGF β binding protein 2		−1.46±0.20
1367650	Rn.1256	lipocalin 7 (glucocorticoid-inducible protein)		−2.09±0.81
1369519	Rn.10918	endothelin 1		−1.56±0.50
1368983	Rn.10148	heparin-binding EGF-like growth factor		−1.50±0.32
1379375	Rn.10999	Platelet derived growth factor α		−1.39±0.14
Receptors
1369146a	Rn.91370	Aryl hydrocarbon receptor	1.96±0.20	1.79±0.19
1367940	Rn.12959	chemokine orphan receptor 1	2.33±0.71
1368742	Rn.10680	complement component 5, receptor 1		2.03±0.89
1387273	Rn.10072	interleukin 1 receptor-like 1		1.55±0.22
1367619	Rn.102356	progesterone receptor membrane component 1		1.49±0.15
1367636	Rn.270	insulin-like growth factor 2 receptor		1.45±0.11
1370249	Rn.1820	benzodiazepin receptor		1.42±0.20
1371840	Rn.4102	endothelial differentiation sphingolipid G-protein-coupled receptor 1	−4.15±2.29
1370462	Rn.92304	Hyaluronan mediated motility receptor (RHAMM)	−3.08±0.93
1373661a	Rn.44431	Chemokine receptor (LCR1)	−1.83±0.54
1373803a	Rn.2178	growth hormone receptor (somatotropin receptor precursor)	−1.71±0.18
1371113a	Rn.98672	transferrin receptor	−1.49±0.35
1370541	Rn.10055	nuclear receptor subfamily 1, group D, member 2	−1.45±0.06
1368553	Rn.10631	activin A receptor type II-like 1		−1.38±0.05
Signaling molecules
1370445	Rn.10696	phosphatidylserine-specific phospholipase A1	1.72±0.29	1.70±0.07
1387822	Rn.21925	G-protein α11 subunit	1.52±0.11
1368332	Rn.25736	guanylate binding protein 2, interferon- inducible	2.25±0.23
1368144	Rn.1892	regulator of G-protein signaling protein 2		2.20±0.61
1372031	Rn.14763	Dab2: Disabled homolog 2, mitogen- responsive phosphoprotein		1.75±0.47
1370942	Rn.23055	RAS p21 protein activator 3 (49%)		1.73±0.63
1383180	Rn.4016	protein phosphatase 1, regulatory (inhibitor) subunit 2		1.53±0.21
1369294	Rn.10728	bone marrow stromal cell antigen 1 (cyclic ADPribose metabolism)		1.51±0.27
1371353	Rn.107103	sequestosome 1		1.37±0.05
1372017	Rn.9090	Direct IAP binding protein with low pI		1.37±0.12
1373658	Rn.19950	Rac GTPase-activating protein 1	−5.44±2.20
1375303	Rn.17340	enigma	−2.60±0.94
1371984	Rn.17340	enigma homolog	−2.15±1.01
1371873	Rn.4268	lecuine-rich acidic protein-like protein	−2.04±0.18
1372084	Rn.106043	tyrosine phosphatase type IVA, member 3 isoform 1	−1.63±0.37
1368101	Rn.2892	calmodulin 3	−1.52±0.00
1370829	Rn.8873	farnesyltransferase β subunit		−1.70 ± 0.42
1373082	Rn.94808	Pkia: Protein kinase inhibitor, α		−1.42±0.20
1370012	Rn.73051	prostaglandin I2 synthase		−1.36±0.15
1369097s	Rn.87228	guanylate cyclase 1, soluble,β3		−1.35±0.05
Cell cycle regulators
1387391	Rn.10089	cyclin-dependent kinase inhibitor 1A, p21	3.9±1.10	4.92±2.82
1383485	Rn.91829	Mdm2		1.99±0.36
1367764	Rn.5834	cyclin G1		1.56±0.26
1373823	Rn.6116	cell division control protein CKS2	−4.08±1.24	−1.83±0.19
1367671	Rn.223	Proliferating cell nuclear antigen	−2.01±0.25	−1.52±0.15
1373557	Rn.8341	replication licensing factor MCM4	−2.48±0.63	−1.55±0.12
1375532	Rn.3272	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	−1.83±0.55	−1.47±0.13
1374775	Rn.12774	cell proliferation antigen Ki-67	−20.5±15.0
1367776	Rn.6934	cell division cycle 2 homolog A	−4.74±0.86
1372685	Rn.25026	cyclin-dependent kinase inhibitor 3	−4.71±1.18
1370346	Rn.9232	Cyclin B1	−3.79±1.35
1389566	Rn.23351	strong similarity to cyclin B2	−3.68±0.88
1388395	Rn.1040	Putative lymphocyte G0/G1 switch protein 2	−2.53±1.25
1374449	Rn.3246	cell division cycle associated 3; gene rich cluster, C8 gene;	−2.31±0.29
1371074a	Rn.33226	mini chromosome maintenance deficient 6	−2.25±0.64
1367894	Rn.772	growth response protein (CL-6)	−1.91±0.20
1370294a	Rn.9262	cell cycle protein p55CDC	−1.81±0.37
1372406	Rn.12916	replication licensing factor MCM3	−1.63±0.17
1367657	Rn.1000	B-cell translocation gene 1	−1.29±0.11
1369935	Rn.3483	cyclin D3		−1.39±0.21
Cytoskeletal proteins and their regulators
1372750	Rn.2743	Follistatin	1.91±0.20	2.30±0.87
1388460	Rn.8945	macrophage capping protein	2.10±0.07
1371618s	Rn.8216	tubulin, β3	1.93±0.32
1386857	Rn.555	stathmin 1	−3.64±0.60	−1.96±0.39
1367785	Rn.31788	Calponin 1	−2.04±0.21	−1.53±0.26
1371339	Rn.11675	cofilin 1	−2.76±1.35
1388718	Rn.1646	tropomodulin 1	−2.39±0.76
1387373	Rn.48693	myomegalin	−1.79±0.59
1370875	Rn.773	villin 2	−1.52±0.11
1370949	Rn.9560	myristoylated alanine rich protein kinase C substrate	−1.39±0.21
1368822	Rn.95652	follistatin-like		−1.33±0.16
Cell surface and extracellular matrix proteins
1367581a	Rn.8871	secreted phosphoprotein 1	2.25±0.67	2.19±0.55
1374620	Rn.91235	Ceacam1	2.10±0.17
1388985	Rn.25004	Collagen α1(V) homologue	1.72±0.29
1389966	Rn.2157	Collagen α3 (VI) homologue	1.49±0.13
1393891	Rn.53843	Collagen α1(VIII) homologue		1.32±0.07
1386879	Rn.764	lectin, galactose binding, soluble 3		2.06±0.86
1368187	Rn.13778	glycoprotein (transmembrane) nmb		2.05±0.76
1367784a	Rn.1780	clusterin		1.91±0.20
1368474	Rn.11267	Vascular cell adhesion molecule 1		1.80±0.25
1370043	Rn.5789	activated leukocyte cell adhesion molecule		1.37±0.16
1392784	Rn.52228	growth arrest specific 6		1.35±0.11
1369943	Rn.10	tissue-type transglutaminase	−2.04±0.48	−1.81±0.25
1388111	Rn.54384	elastin	−1.80±0.39	−3.23±2.46
1368171	Rn.11372	lysyl oxidase	−1.64±0.31	−1.69±0.40
1387850	Rn.44829	transmembrane protein with EGF-like and two follistatin-like domains 1	−3.21±1.23
1388961	Rn.39792	integrin β1 binding protein (melusin) 2	−3.00±1.84
1370937a	Rn.54492	integrin α7	−2.00±0.71
1373897	Rn.11362	lamin B1	−2.99±0.31
1373439	Rn.6499	lamin B receptor	−1.52±0.11
1381504	Rn.45067	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1)	−1.42±0.10
1373401	Rn.12723	tenascin C		−2.49±1.37
1369736	Rn.19723	Epithelial membrane protein 1		−1.80±0.31
1387280a	Rn.32261	tumor-associated protein 1		−1.57±0.32
1367880	Rn.774	laminin, β2		−1.39±0.21
1369955	Rn.117	collagen, type V, α1		−1.35±0.11
Muscle protein and contractile proteins
1368415	Rn.9692	Myosin heavy chain, skeletal muscle, perinatal	−14.38±4.05
1367928	Rn.48663	myosin heavy chain, polypeptide 7, cardiac muscle, β	−3.87±2.42
1371293	Rn.23925	Myosin light chain 1, atrial isoform	−4.83±1.98
1367572	Rn.1955	myosin, light chain polypeptide 3	−2.57±1.50
1376789	Rn.43838	myosin-light-chain kinase	−2.12±0.82
1388298	Rn.6870	Myosin regulatory light chain 2, smooth muscle isoform	−1.38±0.05
1369928	Rn.82732	actin α 1	−3.05±2.04
1386931	Rn.64141	troponin 1, type 3	−2.88±1.68
1386873	Rn.4035	Troponin I, slow isoform	−2.55±0.94
1388604	Rn.38090	Calsequestrin, cardiac muscle isoform	−3.82±1.91
1371801	Rn.12931	calcineurin-binding protein calsarcin-1; muscle-specific protein; FATZ related protein 2	−3.58±1.81
1368988	Rn.10111	calsequestrin 2	−2.36±1.03
1398243	Rn.11345	cysteine-rich protein 3; muscle LIM protein	−3.17±1.69
1370165	Rn.4123	small muscle protein, X-linked	−2.60±0.94
1368252	Rn.28875	sarcomeric muscle protein	−2.30±0.82
1372527	Rn.3210	Rtn2: Reticulon 2 (Z-band associated protein)	−2.27±0.76
1390049	Rn.34417	four and a half LIM domains 1	−2.12±0.93
1371933	Rn.48693	myomegalin	−1.57±0.29
Channel proteins
1370583s	Rn.82691	P-glycoprotein, multidrug resistance 1	5.02±1.52	4.72±1.64
1368207	Rn.24997	FXYD domain-containing ion transport regulator 5	1.73±0.36
1367959a	Rn.4958	sodium channel, voltage-gated, type I, β		2.89±1.33
1370516	Rn.17317	peptide/histidine transporter PHT2		2.14±0.79
1373054	Rn.97686	Ctl1: Transporter-like protein		1.43±0.23
1367683	Rn.2949	karyopherin (importin) α2	−1.62±0.0	−1.64±0.31
1369960	Rn.3828	FXYD domain-containing ion transport regulator 1	−2.60±1.27
1368965	Rn.10826	monocarboxylate transporter	−2.36±0.65
1386901	Rn.3790	fatty acid binding/transport protein (cd36 antigen)	−2.60±1.52
1367660	Rn.32566	fatty acid binding protein 3	−2.06±0.73
1370281	Rn.98269	fatty acid binding protein 5, epidermal	−1.45±0.20
1370850	Rn.3402	sodium channel β3 subunit	−2.63±1.51
1369625	Rn.1618	aquaporin 1	−2.38±1.27
1369065a	Rn.2305	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	−1.87±0.70
1371883	Rn.34134	solute carrier family 1, member 3	−1.85±0.23
1389967	Rn.3366	ADP-ribosylation-like factor 6- interacting protein	−1.50±0.15
1398370	Rn.45761	rexo70		−1.82±0.45
1389986	Rn.58137	synaptic vesicle glycoprotein 2 b		−1.46±0.24
Protease or protease inhibitors
1368590	Rn.52536	matrix metalloproteinase 16	1.79±0.19
1368530	Rn.33193	matrix metalloproteinase 12		2.15±0.82
1368512a	Rn.53979	aminopeptidase A		2.24±0.92
1387005	Rn.11347	cathepsin S		2.24±0.92
1368280	Rn.11559	cathepsin C		2.01±0.54
1368215	Rn.43558	ceroid-lipofuscinosis, neuronal 2		1.42±0.18
1369977	Rn.107213	ubiquitin carboxy-terminal hydrolase L1		1.39±0.21
1368544a	Rn.86956	nucleolar protein 3 (apoptosis repressor with CARD domain)		1.32±0.09
1389408	Rn.99540	neural precursor cell expressed, developmentally down-regulated gene 4A	−5.78±0.52	−3.55±1.36
1372440	Rn.2271	serine (or cysteine) proteinase inhibitor, clade E, member 2	−1.60±0.48	−1.80±0.25
1370064	Rn.11045	presenilin-2	−1.42±0.20	−1.38±0.05
1387804	Rn.40636	muscle ring finger protein 1; ring finger protein 28	−1.97±0.56
1368961	Rn.22562	Matrix metalloproteinase 23		−1.28±0.05
1368519	Rn.29367	serine (or cysteine) proteinase inhibitor, member 1		−1.75±0.50
Nucleic acid metabolism
1368311	Rn.9836	O6-methylguanine-DNA methyltranferase	1.97±0.17	1.36±0.15
1387659	Rn.24783	guanine deaminase		1.91±0.27
1371862	Rn.22094	Ribonucleoside-diphosphate reductase M1 chain (Ribonucleotide reductase large chain).	−2.64±0.15
1387865	Rn.6102	Deoxyuridinetriphosphatase (dUTPase)	−1.69±0.15
1373772	Rn.6955	DNA (cytosine-5)-methyltransferase 1	−1.63±0.11
Chromosomal or DNA binding proteins
1388309	Rn.83614	non-histone chromosomal architectural protein HMGI-C	1.75±0.22
1374293	Rn.40496	Histone H2A.l		1.49±0.22
1367676	Rn.2874	high mobility group box 2	−2.93±0.19	−1.56±0.28
1368136	Rn.3364	lamina-associated protein 2	−2.04±0.21	−1.73±0.38
1386861	Rn.3636	H2A histone family, member Z	−1.62±0.09	−1.30±0.04
1388827	Rn.100938	H2A histone family, member V (predicted)	−1.48±0.24
1372516	Rn.8601	kinesin-like 4; Kid;	−2.89±0.34
1388135	Rn.40389	p32-subunit of replication protein A	−2.00±0.11
1371887	Rn.13669	high-mobility group (nonhistone chromosomal) protein 4	−1.66±0.17
1371352	Rn.3517	high mobility group protein 17	−1.58±0.19
1368042a	Rn.4121	high mobility group box 1	-1.39±0.14
1388504	Rn.3991	RAD21 homolog; protein involved in DNA double-strand break repair; nuclear matrix protein 1	−1.46±0.06
1369996	Rn.28212	polymerase II	−1.37±0.05
1367666	Rn.23677	heterogeneous nuclear ribonucleoprotein H1		−1.36 ± 0.15
Transcription factors
1387087	Rn.6479	CCAAT/enhancer binding protein (C/EBP) β		1.50±0.26
1376569	Rn.114645	Kruppel-like factor 2	−1.38±0.11	−1.95±0.28
1389555	Rn.14867	transcription factor 19 (SC1)	−3.03±0.61
1389528s	Rn.93714	v-jun sarcoma virus 17 oncogene homolog	−1.72±0.26
1388426	Rn.95306	sterol regulatory element binding factor 1	−1.57±0.32
1387769a	Rn.2760	Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	−1.46±0.20
1367664	Rn.3789	ankyrin-like repeat protein		−1.99±0.91
1374335	Rn.8701	GATA binding protein 6		−1.44±0.09
Protein synthesis and conformation
1371378	Rn.4113	Protein translation factor SUI1 homolog	−1.26±0.05
1371421	Rn.98472	translation elongation factor eEF-1 α chain	−1.81±0.56
1372431	Rn.105932	mitochondrial ribosomal protein L12	−1.37±0.12
1370007	Rn.39305	protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)		−1.38±0.05
Stress genes
1387047	Rn.20155	heat shock 27kD protein family, 3	−3.79±2.62
Miscellaneous
1388674	Rn.36610	tumor protein, translationally-controlled 1	3.08±0.11	2.46±0.70
1370459	Rn.38451	A5D3 protein	2.46±0.0	1.45±0.16
1369008a	Rn.11005	olfactomedin related ER localized protein	1.78±0.12	1.57±0.06
1373932	Rn.98491	Cybb: Endothelial type gp91-phox gene		2.93±1.42
1368006	Rn.24799	lysosomal-associated protein transmembrane 5		2.39±0.76
1389210	Rn.14256	lymphocyte cytosolic protein 1		2.36±0.84
1390383	Rn.101967	Adipose differentiation-related protein		1.73±0.41
1371131a	Rn.2758	upregulated by 1,25-dihydroxyvitamin D- 3		1.69±0.15
1368013	Rn.19672	Smhs1 protein		1.66±0.42
1387946	Rn.3251	peptidylprolyl isomerase C-associated protein		1.59±0.32
1367881	Rn.53971	protein tyrosine phosphatase, non- receptor type substrate homolog		1.51±0.27
1387081	Rn.6133	reticulocalbin 2		1.42±0.18
1390325	Rn.11414	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (CD38)		1.38±0.05
1387770	Rn.3867	Interferon α-inducible protein 27-like		1.23±0.0
1370697a	Rn.107975	nexilin	−1.63±0.18	−1.64±0.31
1374672	Rn.3434	cardiac ankyrin repeat kinase	−7.97 ± 7.22
1370805	Rn.8163	melanocyte-specific gene 1 protein	−5.97±2.34
1390137	Rn.20235	TRAF4 associated factor 1 homolog	−5.42±3.32
1372886	Rn.39396	Transforming acidic coiled-coil- containing protein 3	−3.71±1.36
1377190	Rn.12822	transcription activator of D-serine dehydratase	−3.66±1.29
1387957a	Rn.24200	SH3-domain kinase binding protein 1	−3.23 ± 1.50
1372065	Rn.4077	ADP-ribosyltransferase 3	−2.60±0.94
1376084a	Rn.24582	extra spindle poles like 1	−2.47±0.54
1372296	Rn.4128	SH3 domain-binding glutamic acid-rich protein (21-glutamic acid-rich protein)	−2.44±1.07
1372646	Rn.16593	esophageal cancer related gene 4 protein	−1.99±0.34
1368174	Rn.10994	EGL nine homolog 3 (C. elegans)	−1.85±0.39
1368566a	Rn.6452	MIPP65 protein (mitochondrial phosphoprotein)	−1.85±0.40
1370828	Rn.17310	zinc finger, DHHC domain containing 2	−1.85±0.28
1372106	Rn.7379	pincher	−1.61±0.34
1370176	Rn.26957	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3	−1.57±0.29
1374951	Rn.45300	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	−1.50±0.26
1371365	Rn.3460	ubiquitin carrier protein E2	−1.48±0.24
1370189	Rn.8538	splicing factor, arginine/serine-rich (transformer 2 Drosophila homolog) 10	−1.42±0.18
1371358	Rn.3380	synaptic glycoprotein SC2 (32%)	−1.42±0.20
1370252	Rn.13633	Esau	−1.39±0.14
1370062	Rn.2084	hypoxia induced gene 1	−1.39±0.14
1376749	Rn.12119	osteoinductive factor	−1.32±0.09
1371298	Rn.6171	H19 fetal liver mRNA	−1.26±0.05
1376198	Rn.40141	visceral adipose tissue-specific transmembrane protein OL-16		−1.79 ± 0.74
1370248	Rn.839	FXYD domain-containing ion transport regulator 6		−1.52 ± 0.42
1367604	Rn.4267	cysteine-rich protein 2		−1.50 ± 0.23
1373195	Rn.9404	orphan seven transmembrane receptor		−1.42 ± 0.10
1370000	Rn.41602	NEFA precursor		−1.39 ± 0.21
1367744	Rn.11984	melanoma antigen, family D, 2		−1.33 ± 0.16