TABLE 2.
Relative expression of phenotype-specific gene markers in the whole tibia normalized to 18 S rRNA
Treatment | Runx2/Cbfa1 | Dlx5 | Osteocalcin | α1 (I) collagen | aP2 |
---|---|---|---|---|---|
Control | 9.3 ± 1.8 | 9.0 ± 1.9 | 7.6 ± 3.7 | 10.3 ± 0.7 | 3.2 ± 0.2 |
Rosiglitazone | 6.4 ± 0.1a | 6.4 ± 0.7a | 7.4 ± 0.8 | 5.5 ± 1.1a | 13.5 ± 1.9a |
Ratio (rosiglitazone/vehicle) | 0.6 | 0.7 | 1.0 | 0.6 | 3.4 |
Data are given as mean ± SD; n = 4 animals per group.
P < 0.05 vs. control.