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. 2007 May 1;21(9):1075–1085. doi: 10.1101/gad.417707

Figure 6.

Figure 6.

Sequence conservation and functional domains of the newly characterized NMD factors. (A) Schematic representation of the human NAG, which is the homolog of C. elegans SMGL-1. Black boxes represent the regions of sequence conservation within proteins; the level of conservation is indicated. WD40 domains within the N terminus of the protein are indicated by brackets above the protein. (B) Schematic representation of the human DHX34, which is the homolog of C. elegans SMGL-2. Black boxes represent the regions of sequence conservation within proteins; the level of conservation is indicated. Functional domains associated with ATP-dependent RNA helicases (DEXDc, HELICc, PFAM:HA2, and PFAM:DUF 1605) are indicated by brackets above the protein.