Table 2.

The practical impact on conclusions of three meta-analyses submitted to publication bias adjustment.

Authors	Topic	Comparison	Outcome	Non-adjusted meta-analysis conclusion (transcription)	Adjusted meta-analysis conclusion
Hopkins 14	Antibiotic prophylaxis regimens for cesarean section	Any single dose of systemic antibiotic versus any multiple dose	Endometritis	"There is no evidence from this meta-analysis to recommend multiple doses of antibiotics"	Any single dose systemic regimen (pre, post or intra-operative) may be more effective than any multiple dose regimen
Hodnett 15	Continuous support for women during childbirth	Continuous one-to-one intrapartum support versus usual care	Cesarean birth	"Women who had continuous, one-to-one support during labour were less likely to have a caesarean birth"	Continuous support may not reduce the occurrence of cesarean birth comparing to usual care.
Cheng 16	Interventions for emergency contraception	Mifepristone mid-dose (25–50 mg) versus low-doses (≤ 10 mg)	Observed number of pregnancies	"Although the overall meta-analysis shows fewer pregnancies with the mid-dose... when the analysis is limited to the five trials with adequate allocation concealment...this effect is no longer evident"	Mifepristone mid-doses (25–50 mg) may not be more effective than low doses (≤ 10 mg)