Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Prostanoid hypothesis for the cardiovascular adverse effects of cyclooxygenase (COX)-2 inhibitors. When COX-2 is inhibited, more leukotriene B4 and thromboxane A2 (TXA2) are produced. This tip of balance leads to an increased risk for cardiovascular adverse events.
