Table 1.

PS-ODNs targeting the M. tuberculosis 30, 32A, and 32B protein gene transcripts

mRNA target 5′→3′	PS-ODN 5′→3′
30-kDa protein
30:1–24	AATCTTTCGGCTCACGTCTGTCAT
30:HP2/HP1	GCGCATATGCGCAATCTTTCGGCTCACGTCTGTCATGCGCGCGC
30:1–24-MM	AtTCaTTtGGtTCtCGaCTcTCtT
30:HP2/HP1-MM	GCGCATATGCGCAtTCaTTtGGtTCcCGaCTcTCtTGCGCGCGC
32A-kDa protein
32A:1–24	ACGAACCCTGTCAACAAGCTGCAT
32A:HP2/HP1	GCGCATATGCGCACGAACCCTGTCAACAAGCTGCATGCGCGCGC
32A:1–24-MM	AgGAtCCtTGaCAtCAtGCaGCtT
32A:HP2/HP1-MM	GCGCATATGCGCAtGAtCCaTGcCAgCAtGCaGCtTGCGCGCGC
32B-kDa protein
32B:1–24	TCGCACCTGTTCGAAGAACGTCAT
32B:HP2/HP1	GCGCATATGCGCTCGCACCTGTTCGAAGAACGTCATGCGCGCGC
32B:1–24-MM	TgGCtCCaGTaCGtAGtACcTCtT
32B:HP2/HP1-MM	GCGCATATGCGCTgGCtCCaGTaCGtAGtACcTCtTGCGCGCGC

HP2/HP1, hairpin 2 at 5′ end and hairpin 1 at 3′ end; nucleotides comprising hairpins are in bold italics. MM, mismatched nucleotide(s), indicated by lowercase letters.