Table 2.
Baseline and 2-year follow-up cognitive performance scores on nondemented subjects in longitudinal study
| Subject groups
|
||
|---|---|---|
| With APOE-4 (n = 10) | Without APOE-4 (n = 10) | |
| Mini-mental state exam | ||
| Baseline | 28.0 ± 1.3 | 29.0 ± 1.3 |
| Follow-up | 28.0 ± 2.1 | 28.7 ± 1.3 |
| Delayed paragraph recall | ||
| Baseline | 14.7 ± 6.6 | 18.4 ± 4.3 |
| Follow-up | 13.6 ± 7.5 | 20.2 ± 8.3 |
| Buschke-Fuld total recall* | ||
| Baseline | 87.9 ± 14.0 | 95.2 ± 20.9 |
| Follow-up | 70.4 ± 29.4 | 94.2 ± 21.5 |
| Benton visual errors | ||
| Baseline | 4.7 ± 2.6 | 6.1 ± 3.1 |
| Follow-up | 5.4 ± 3.7 | 3.8 ± 2.1 |
An ANCOVA model using follow-up scores as outcomes and baseline scores as covariates yielded no significant difference between groups in any of the measures. Values are reported as mean ± SD or number (percent).
Baseline vs. follow-up for APOE-4 carriers: t = 2.5, df = 9, P = 0.036 (uncorrected).