Fig. 4.

Synergistic effect of dexamethasone and IL-1β, or IL-6, on FPR mRNA expression. Saos-2 cells were incubated for 24 h in the absence and presence of dexamethasone (Dex; 0.1 μM) and IL-1β (10 ng/ml) or IL-6 (1, 10, and 100 ng/ml). Total RNA was then extracted and PCR performed for FPR (a) or FPRL-1 (b) gene expression. Data report the densitometric analysis of three independent experiments, mean ± SEM of values shown as percent of control group (vehicle only). P < 0.05, Dex-treated vs. control cells.