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Analysis of corticotroph cell density in wild-type (WT), heterozygote and ANXA1 null mice. Immunofluorescence detection of adrenocorticotrophic hormone-labelled corticotrophs in (a) wild-type and (b) ANXA1 null pituitary and (c) quantification of corticotroph cell density. Filled bars, male; open bars, female corticotrophs. Data are mean ± SEM (n = 4 for all groups). **P < 0.05 versus wild-type of the same gender. Scale bars = 50 μm.
