TABLE 2.
Pharmacokinetic parameters
Antibiotic and dose (mg/kg) | Cmax (μg/ml)a | AUC (0 to 6 h; μg·h/ml) | Trough (6 h; μg/ml) |
---|---|---|---|
Ciprofloxacin | |||
25 | 6.6 | 6.6 | 1 |
50 | 10.7 | 14.1 | 1.83 |
100 | 20 | 37.7 | 1.67 |
Doxycycline | |||
25 | 4 | 13.7 | 1.33 |
50 | 6.7 | 23.4 | 1.67 |
100 | 12 | 57.2 | 6 |
Cmax, maximum concentration of drug in serum.