TABLE 2.

Annual distribution of 16 clones among a sample of 739 Streptococcus pyogenes isolates with the MLS_B-resistant phenotype^a

Clone	No. of isolates
	1999	2000	2001	2002	2003	2004	2005	Total
emm11/T11/ST403b	0	0	0	5	103	202	153	463
emm28/T28/ST52, bacitracin resistant	3	8	13	20	12	12	47	115
emm28/T28/ST52, bacitracin susceptible	10	1	1	1	6	7	7	33
emm22/T12/ST46c	12	9	10	6	8	6	11	62
emm77/T28/ST63d	12	5	4	1	0	1	1	24
emm73/T13/ST331e	0	4	3	0	4	1	1	13
emm94/TB3264/ST89	2	1	0	0	0	3	2	8
emm89/TB3264/ST101	0	0	0	0	0	0	4	4
emm58/T NT/ST19	0	0	0	0	0	0	3	3
emm12/T12/ST36	1	1	0	1	0	0	0	3
emm6/T6/ST37	0	0	1	0	0	1	1	3
emm2/T2/ST55	0	0	0	0	0	1	1	2
emm4/T4/ST39f	0	0	0	0	0	2	0	2
emm81/TB3264/ST117	1	0	0	0	0	0	0	1
emm68/T3,B3264/ST247	0	0	1	0	0	0	0	1
emm75/T8,25/ST150	0	1	0	0	0	0	0	1
emm102/T4/ST376	1	0	0	0	0	0	0	1
Total	42	30	33	34	133	236	231	739

^aThe two subclones of the emm28/T28/ST52 clone are represented separately. Each clone was designed with the most prevalent T type found in that clone.

^bTwo isolates (ST403/T11) were emm nontypeable(NT). T11 (n = 413), the T5,8,9,imp19,25,27 complex (n = 28), T28 (n = 2), and T nontypeable (n = 20) were also included. A total of 448 ST403 isolates (which did not amplify the yqiL allele), 9 ST21 isolates, and 6 ST20 isolates were included.

^cTB3264 (n = 3); T3,5 (n = 1), and T nonetypeable (n = 2). The remaining isolates were of the T12 type and belonged to the T3,12,13,B3264 complex, which comprised isolates that were mainly T12 alone (n = 40).

^dAll isolates belonged to the T9,13,28 complex, and all but one (T13,9) agglutinated with the T28 type. A total of 23 ST63 isolates and 1 ST369 isolate were included.

^eAll isolates belonged to the T3,13,B3264 complex, and all agglutinated with the T13 type.

^fOne ST38 isolate and one ST39 isolate were included.