TABLE 2.

IC₅₀s and IC₉₀s obtained with fresh clinical isolates after 48 and 72 h of incubation by the SYBR green I and HRPII assays

Patient no.	Chloroquine						Mefloquine
	SYBR green I				HRPII ELISA, 72 h		SYBR green I				HRPII ELISA, 72 h
	48 h		72 h				48 h		72 h
	IC50 (nM)	IC90 (nM)	IC50 (nM)	IC90 (nM)	IC50 (nM)	IC90 (nM)	IC50 (nM)	IC90 (nM)	IC50 (nM)	IC90 (nM)	IC50 (nM)	IC90 (nM)
1	58 ± 39	482 ± 191	12.5 ± 0	24 ± 14	13 ± 0	14 ± 2	33 ± 21	146 ± 20	14 ± 6	131 ± 23	5 ± 0.5	11 ± 1
2	24 ± 6	377 ± 4	20 ± 5	43 ± 12.5	27 ± 6	77 ± 7	42 ± 15	101 ± 32	23 ± 3	69 ± 11	14 ± 2	68 ± 1
3	38 ± 4	77 ± 12	35 ± 1	80 ± 15.5	43 ± 4	95 ± 10	37 ± 8	108 ± 16	41 ± 10	110 ± 15	36 ± 11	88 ± 6
4	36 ± 1	97 ± 1	37 ± 1	53 ± 13	NDa	ND	34 ± 6	94 ± 14	43 ± 8	109 ± 13	ND	ND
5	67 ± 3	160 ± 18	53 ± 13	165 ± 25.5	67 ± 37	516 ± 37	28 ± 4	86 ± 19	64 ± 7	167 ± 18	16 ± 10	53 ± 39
6	ND	ND	56 ± 5	140 ± 14	15 ± 1	39 ± 3	ND	ND	ND	ND	27 ± 3	64 ± 4
7	ND	ND	243 ± 39	374 ± 37	258 ± 20	354 ± 31	ND	ND	42 ± 14	114 ± 38	16 ± 11	49 ± 16
8	164 ± 1	478 ± 190	437 ± 90	679 ± 120	ND	626 ± 2	18 ± 3	60 ± 13	20 ± 13	49 ± 16	9 ± 0.5	22 ± 2
9	390 ± 55	732 ± 19	370 ± 35	742 ± 11	256 ± 73	538 ± 109	43 ± 15	106 ± 21	43 ± 10	115 ± 15	8 ± 0.5	56 ± 3
10	ND	ND	410 ± 73	ND	366 ± 21	707 ± 27	ND	ND	21 ± 4	59 ± 14	18 ± 1	34 ± 0.5

^aND, the inhibitory concentration was not determined due to insufficient growth of the parasites or a low correlation coefficient.