TABLE 1.
Distributions of fluconazole MICs for different Candida species strains under planktonic or biofilm (sessile-cell) growth conditions
| Species | No. of isolates tested | Type of MICa | No. of isolates for which indicated MIC (μg/ml) was:
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | >1,024 | |||
| C. albicans | 12 | MIC for planktonic cells | 3 | 4 | 1 | 3 | 1 | ||||||||
| MIC50 for sessile cells | 1 | 1 | 2 | 1 | 7 | ||||||||||
| MIC80 for sessile cells | 12 | ||||||||||||||
| C. parapsilosis | 12 | MIC for planktonic cells | 1 | 4 | 4 | 3 | |||||||||
| MIC50 for sessile cells | 2 | 10 | |||||||||||||
| MIC80 for sessile cells | 12 | ||||||||||||||
| C. tropicalis | 10 | MIC for planktonic cells | 1 | 6 | 1 | 2 | |||||||||
| MIC50 for sessile cells | 2 | 8 | |||||||||||||
| MIC80 for sessile cells | 10 | ||||||||||||||
| C. glabrata | 9 | MIC for planktonic cells | 1 | 2 | 5 | 1 | |||||||||
| MIC50 for sessile cells | 1 | 8 | |||||||||||||
| MIC80 for sessile cells | 9 | ||||||||||||||
a
MIC50s and MIC80s were determined by measuring XTT activity reduction.