TABLE 5.

Activities of SSAT and ODC in the intestinal epithelia of animals treated with CGC-11157 for various times^a

Treatment	Activity (nmol/min/mg protein) ± SD		ODC/SSAT ratio
	SSAT	ODC
Control	0.033 ± 0.013	0.049 ± 0.022	1.48
i.p., 48 h	0.081 ± 0.026	0.079 ± 0.047	0.97
i.p., 72 h	0.034 ± 0.011	0.034 ± 0.011	1.00
i.p., 96 h	0.040 ± 0.015	0.160 ± 0.169	4.00
p.o., 48 h	0.090 ± 0.016	0.089 ± 0.070	0.99
p.o., 72 h	0.036 ± 0.010	0.056 ± 0.029	1.55
p.o., 96 h	0.040 ± 0.014	0.116 ± 0.048	2.90

^aDosing was once per day. i.p. indicates 0.2 mg of CGC-11157 administered via intraperitoneal injection; p.o. indicates 2 mg of CGC-11157 administered per os.