TABLE 3.
Distribution of serotypes, PFGE types and subtypes, STs, and resistance to antimicrobial agents among tetracycline-resistant isolates
| Serotype | PFGE (sub)type(s) (no. of isolates) | STa | Drug(s) to which isolate(s) was resistantb | International clone |
|---|---|---|---|---|
| 3 | 55a (2) | ND | ||
| 3 | 55a (1) | ND | DOX | |
| 3 | 1a (1) | 423 | CHL | |
| 4 | 56a (1) | ND | ||
| 6A | 31a (1) | 72 | MIN | |
| 6A | 32a (1) | 440 | MIN | |
| 6A | 24a (1) | 490 | DOX, ERY, CLI | |
| 6A | 24b (1), 29a (1) | 490 | SXT | |
| 6A | 24c (1) | 490 | MIN, SXT | |
| 6A | 25a (1), 27a (1) | 490 | ||
| 6A | 28a (1) | 490 | CHL | |
| 6A | 26a (1) | 490 | MIN, ERY, CLI, SXT | |
| 6A | 26a (1) | 1049 | MIN, DOX, ERY, CLI, SXT | |
| 6A | 30a (2) | 2185 | DOX | |
| 6A | 30a (1) | 2185 | DOX, MIN | |
| 6A | 30a (1) | 2185 | DOX, MIN, SXT | |
| 6A | 30a (1) | 2185 | DOX, MIN, ERY, CLI | |
| 6A | 30b (1) | 2184 | DOX, MIN | |
| 6B | 35a (1) | 90 | MIN, PEN, CHL, SXT | Spain6B-2 |
| 6B | 34b (1) | 273 | DOX, MIN, ERY, CLI | Greece6B-22 |
| 6B | 34c (1) | 273 | MIN, ERY, CLI | Greece6B-22 |
| 6B | 34a (1) | 273 | MIN, ERY, CLI, CHL | Greece6B-22 |
| 6B | 33a (5), 33e (1) | 315 | DOX, MIN, ERY, CLI, SXT | Poland6B-20 |
| 6B | 33f (1) | 315 | MIN, ERY, CLI, SXT | Poland6B-20 |
| 6B | 33a (1), 33i (1) | 315 | MIN, ERY, CLI | Poland6B-20 |
| 6B | 33a (2), 33f (1), 33h (1) | 315 | DOX, MIN, ERY, CLI | Poland6B-20 |
| 6B | 33d (1) | 315 | DOX, ERY, CLI | Poland6B-20 |
| 6B | 33a (1) | 315 | DOX, MIN, CLI, CHL | Poland6B-20 |
| 6B | 33g (1) | 315 | DOX, MIN, PEN, ERY, CLI, SXT | Poland6B-20 |
| 6B | 33b (1) | 1032 | DOX, MIN, MEM, ERY, CLI | SLV Poland6B-20 |
| 6B | 33b (1) | 1032 | DOX, MIN, ERY, CLI | SLV Poland6B-20 |
| 6B | 33c (1) | 1053 | DOX, ERY, CLI, SXT | SLV Poland6B-20 |
| 6B | 34a (1) | 1490 | MIN, ERY, CLI, CHL | SLV Greece6B-22 |
| 6B | 34a (1) | 1490 | ERY, CLI, CHL | SLV Greece6B-22 |
| 6B | 33a (1) | 1505 | ERY, CLI, SXT | SLV Poland6B-20 |
| 6B | 16b (1) | 2138 | ||
| 7F | 57a (1) | ND | MIN | |
| 8 | 58a (1) | ND | ||
| 9N | 59a (2) | ND | ||
| 9N | 60a (2) | ND | ||
| 10A | 61a (1) | ND | ||
| 11A | 63a (1) | 62 | DOX, MIN, ERY, SXT | |
| 11A | 62a (1) | 1010 | DOX, MIN | |
| 11A | 64a (1) | ND | DOX, MIN, CHL | |
| 11A | 65a (1) | ND | CHL | |
| 12F | 66a (1) | ND | CHL | |
| 14 | 18a (1) | 124 | CHL | |
| 14 | 19a (1) | 124 | DOX, MIN, ERY, CHL | |
| 14 | 20a (1), 21a (1) | 124 | ||
| 14 | 14a (3) | 143 | DOX, MIN, PEN, ERY, CLI, SXT | |
| 14 | 14a (1) | 143 | DOX, MIN, PEN, ERY, CLI, TEL | |
| 14 | 14a (1) | 143 | DOX, MIN, PEN, CTX, ERY, CLI | |
| 14 | 14b (1) | 143 | DOX, MIN, PEN, ERY, CLI | |
| 14 | 15a (1) | 143 | PEN, ERY, CLI | |
| 14 | 22a(1) | 156 | PEN, ERY, CLI, SXT | Spain9V-3 |
| 14 | 23a (1) | 378 | ||
| 14 | 14a (1) | 1477 | DOX, MIN, PEN, ERY, CLI | |
| 14 | 16a (1) | 2138 | ||
| 14 | 17a (1) | 2139 | ||
| 15A | 67a (1) | 63 | DOX, MIN, ERY, CLI | Sweden15A-25 |
| 15A | 70a (1) | 124 | DOX, MIN, SXT | |
| 15A | 68a (1) | 410 | DOX, CHL | |
| 15A | 69a (1) | 410 | CHL, SXT | |
| 15A | 16b (1) | 2138 | ||
| 15B/C | 71a (1) | ND | ERY, CLI, SXT | |
| 15B/C | 72a (3) | ND | ||
| 15B/C | 73a (1) | ND | MIN, CHL | |
| 15F | 74a (1) | ND | MIN | |
| 18B | 76a (1) | ND | ||
| 18C | 1a (1) | 423 | DOX, CHL | |
| 18C | 75a (1) | 1016 | CHL, SXT | |
| 18C | 75b (1), 75c (1) | 1016 | ||
| 19A | 77a (1) | 276 | ERY, SXT, RIF | |
| 19A | 77b (1) | 276 | ERY, CLI | |
| 19A | 77b (1) | ND | MIN, PEN, ERY, CLI, SXT | |
| 19A | 77b (1) | ND | PEN, ERY, CLI, SXT | |
| 19A | 78a (2) | 1625 | SXT | |
| 19F | 13a (1) | 81 | PEN, CHL, SXT | Spain23F-1 |
| 19F | 7a (1) | 179 | DOX, ERY, CLI | SLV Portugal19F-21 |
| 19F | 6a (1) | 236 | DOX, MIN, PEN, CTX, ERY, SXT | Taiwan19F-14 |
| 19F | 9a (1) | 236 | SXT | Taiwan19F-14 |
| 19F | 11a (1) | 236 | MIN | Taiwan19F-14 |
| 19F | 8a (1) | 257 | ERY, CLI, SXT | |
| 19F | 5a (1) | 410 | DOX, CHL | |
| 19F | 1a (20) | 423c | CHL | |
| 19F | 10a (1) | 423 | CHL | |
| 19F | 1a (2) | ND | DOX, MIN, CHL | |
| 19F | 1a (1) | ND | DOX, CHL | |
| 19F | 1a (1) | ND | MIN, CHL | |
| 19F | 2b(1) | 423 | MIN, CHL | |
| 19F | 1a (7) | ND | CHL, SXT | |
| 19F | 12a (1) | 423 | CHL, SXT | |
| 19F | 1a (1) | ND | DOX, MIN, CHL, SXT | |
| 19F | 1a (3) | 423c | MIN, CHL, SXT | |
| 19F | 2a (1) | 423 | MIN, CHL, SXT | |
| 19F | 1a (2) | 423c | SXT | |
| 19F | 1a (2) | ND | MIN, SXT | |
| 19F | 1a (1) | 423 | ERY | |
| 19F | 1a (1) | ND | CHL, RIF | |
| 19F | 1a (3) | ND | ||
| 19F | 1e (1), 2c (1) | 423 | ||
| 19F | 1b (1) | 423 | DOX, MIN, SXT | |
| 19F | 1c (2) | 423c | SXT | |
| 19F | 1c (1) | ND | CHL, SXT | |
| 19F | 1g (1) | 423 | CHL, SXT | |
| 19F | 1f (1), 1g (1), 1i (1) | 423 | CHL | |
| 19F | 1h (1) | 423 | ||
| 19F | 3a (1) | 1489 | DOX, ERY, CLI | |
| 19F | 1d (1) | 1815 | ||
| 19F | 4a (1) | 2136 | DOX, MIN, SXT | |
| 20 | 79a (1) | ND | ||
| 22F | 80a (1) | ND | CHL | |
| 22F | 81a (1) | ND | ||
| 23F | 52a (1) | 72 | DOX, MIN, ERY, CLI | |
| 23F | 37a (3), 37d (1), 37e (2), 37g (1) | 81 | PEN, CHL, SXT | Spain23F-1 |
| 23F | 37d (1) | 81 | DOX, PEN, CHL, SXT | Spain23F-1 |
| 23F | 37a (2), 37h (1) | 81 | CHL, SXT | Spain23F-1 |
| 23F | 37a (1), 37f (1) | 81 | PEN, ERY, CHL, SXT | Spain23F-1 |
| 23F | 37b (1) | 81 | PEN, SXT | Spain23F-1 |
| 23F | 37c (1) | 81 | PEN, CHL, SXT, LVX | Spain23F-1 |
| 23F | 38a (1) | 81 | PEN, ERY, CLI, CHL, SXT | Spain23F-1 |
| 23F | 54a (1) | 242 | DOX, MIN, PEN, ERY, CLI | Taiwan23F-15 |
| 23F | 47b (2) | 272 | DOX, MIN, PEN, ERY, CLI, CHL, SXT | SLV Poland23F-16 |
| 23F | 47c (2) | 272 | DOX, MIN, PEN, CTX, ERY, CLI, CHL, SXT | SLV Poland23F-16 |
| 23F | 47c (1) | 272 | MIN, PEN, CTX, ERY, CLI, CHL, SXT | SLV Poland23F-16 |
| 23F | 48a (1) | 410 | CHL, SXT | |
| 23F | 1a (1) | 423 | SXT | |
| 23F | 39a (3), 39f (2), 42a (1), 43a (1), 45a (1) | 440 | MIN | |
| 23F | 39a (2), 42b (1), 44a (1) | 440 | ||
| 23F | 39a (1) | 440 | DOX, MIN, CHL | |
| 23F | 39a (1) | 440 | MIN, SXT | |
| 23F | 46a (1) | 440 | MIN, ERY, CLI | |
| 23F | 39a (1), 39c (1), 39e (1), 41a (1) | 602 | ||
| 23F | 39a (1), 39b (1), 40a (1) | 602 | MIN | |
| 23F | 39a (3) | 602 | MIN, SXT | |
| 23F | 37d (1) | 1051 | PEN, CHL, SXT | SLV Spain23F-1 |
| 23F | 51a (1) | 1116 | ||
| 23F | 53a (1) | 1364 | MIN, CHL | |
| 23F | 37e (1) | 1476 | CHL, SXT | SLV Spain23F-1 |
| 23F | 39d (1) | 1479 | MIN, ERY, SXT | |
| 23F | 39d (1) | 1479 | MIN, SXT | |
| 23F | 50a (1) | 2137 | CHL, SXT | |
| 23F | 47a (1) | 2140 | DOX, MIN, PEN, ERY, CLI, CHL, SXT | SLV Poland23F-16 |
| 23F | 49a (1) | 2141 | DOX | |
| 23F | 39a (1) | ND | ||
| 28 | 82a (1), 83a (1) | ND | ||
| 28F | 84a (1) | ND | MIN | |
| 28F | 85a (1) | ND | ||
| 33F | 66b (1) | ND | CHL | |
| 35C | 86a (1) | ND | ||
| 35C | 87a (1) | ND | MIN | |
| 37 | 88a (1) | ND | MIN | |
| 37 | 89a (1) | ND | CHL, SXT | |
| Rough | 90a (1) | 317 | MIN, ERY, CLI, SXT | |
| Rough | 36a (1) | 410 | DOX, CHL |
a
New STs are shown in boldface; allelic profiles are as follows: ST2136, 13-16-19-5-17-20-26; ST2137, 15-17-4-12-6-1-6; ST2138, 2-12-1-18-17-4-14; ST2139, 16-44-1-16-9-11-8; ST2140, 7-13-8-1-10-6-171; ST2141, 10-25-12-1-6-20-28; ST2184, 1-10-9-18-5-1-6; ST2185, 1-10-9-43-5-1-6. ND, not determined.
b
CTX, cefotaxime; CHL, chloramphenicol; CLI, clindamycin; DOX, doxycycline; ERY, erythromycin; LVX, levofloxacin; MEM, meropenem; MIN, minocycline; PEN, penicillin; RIF, rifampin; TEL, telithromycin; SXT, trimethoprim-sulfamethoxazole.
c
ST was determined for selective representative only.