TABLE 2.
Resistance profiles of 69 isolates from patient B
| Isolatea | Genotypeb | Day | Susceptibilityc to the following antimicrobiald (zone inhibition diam range [mm]e)
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β-Lactams
|
Aminoglycosides
|
FQs
|
||||||||
| Pip/Taz (17-18) | Caz (14-18) | Cep (14-18) | Imi (13-16) | Am (14-17) | Gm (12-15) | Nor (12-17) | Clp (15-21) | |||
| 2A5 | a | 0 | S | S | S | S | S | S | S | S |
| 3D1 | * | 2 | S | S | S | S | S | S | S | S |
| 3D10 | a | 2 | S | S | S | S | S | S | S | S |
| 3E2 | b | 2 | S | S | S | S | S | S | S | S |
| 5F2 | b | 7 | S | S | S | S | S | S | S | S |
| 5F8 | * | 7 | S | S | S | S | S | S | S | S |
| 5G3 | * | 7 | S | S | S | S | S | S | S | S |
| 5H6 | * | 7 | S | S | S | S | S | S | S | S |
| 8A2f | a | 9 | S | S | S | S | S | S | S | S |
| 8A12 | a | 9 | S | S | S | S | S | S | I | S |
| 8C4 | * | 9 | S | S | S | S | S | S | S | S |
| 8B11 | * | 9 | S | S | S | S | S | S | S | S |
| 9A1 | * | 12 | S | S | S | S | S | S | S | S |
| 9A3 | c | 12 | S | S | S | S | S | S | S | S |
| 9A7 | * | 12 | S | S | S | S | S | S | S | S |
| 9A10 | * | 12 | S | S | S | S | S | S | S | S |
| 9B2 | * | 12 | S | S | S | S | S | S | S | S |
| 9B5 | c | 12 | S | S | S | S | S | S | S | S |
| 10A6 | * | 13 | S | S | S | S | S | S | S | S |
| 10A9 | * | 13 | S | S | S | S | S | S | S | S |
| 10B1 | * | 13 | S | S | S | S | S | S | S | S |
| 10B3 | * | 13 | S | S | S | S | S | S | S | S |
| 12A3 | * | 15 | S | S | S | S | S | S | S | S |
| 12A7 | * | 15 | S | S | S | S | S | S | S | S |
| 12B2 | * | 15 | S | S | S | S | S | S | S | S |
| 13D3f | a | 16 | S | S | S | S | S | S | I | I |
| 13D6 | * | 16 | S | S | S | S | S | S | I | I |
| 13D11 | * | 16 | S | S | S | S | S | S | S | S |
| 13E1 | * | 16 | S | S | S | S | S | S | S | S |
| 15G2f | a | 20 | S | S | S | S | S | S | R | R |
| 15G10f | a | 20 | S | S | S | S | S | S | I | I |
| 15H5 | * | 20 | S | S | S | S | S | S | S | S |
| 16D2f | a | 21 | S | S | S | S | S | S | I | I |
| 16D5 | a | 21 | S | S | S | S | S | S | S | S |
| 19B1f | a | 28 | S | S | S | S | S | S | I | I |
| 19B3 | * | 28 | S | S | S | S | S | S | S | S |
| 19B6 | * | 28 | S | S | S | S | S | S | S | S |
| 19C2f | a | 28 | S | S | I | S | S | S | I | I |
| 19C5 | * | 29 | S | S | S | S | S | S | S | S |
| 19C7 | * | 29 | S | S | S | S | S | S | S | S |
| 19C12 | a | 29 | S | S | S | S | S | S | I | I |
| 19D9f | a | 29 | S | S | S | S | S | S | R | R |
| 19D10 | a | 30 | S | S | S | S | S | S | I | I |
| 19E1 | a | 30 | S | S | S | S | S | S | I | I |
| 19E2 | a | 30 | S | S | S | S | S | S | S | S |
| 19E12 | * | 30 | S | S | S | S | S | S | I | I |
| 19E9f | a | 30 | S | S | S | S | S | S | S | S |
| 19F1f | a | 30 | S | S | S | S | S | S | I | I |
| 19F2 | * | 30 | S | S | S | S | S | S | I | I |
| 22D2 | * | 33 | S | S | S | S | S | I | S | S |
| 22D6 | * | 33 | S | S | S | S | S | I | S | S |
| 22D9f | a | 33 | S | S | S | S | S | S | S | S |
| 22E1f | a | 33 | S | S | S | S | S | S | S | S |
| 22E3 | * | 33 | S | S | S | S | S | S | S | S |
| 24C5 | * | 34 | S | S | S | S | S | S | S | S |
| 24D1 | * | 34 | S | S | S | S | S | I | S | S |
| 24D5f | a | 34 | S | S | I | S | S | S | R | I |
| 24E1 | a | 34 | S | S | S | S | S | S | I | I |
| 24E2 | a | 34 | S | S | S | S | S | S | I | I |
| 24E5 | * | 34 | S | S | S | S | S | I | S | S |
| 24E6f | a | 34 | S | S | S | S | S | S | I | I |
| 23C5f | a | 35 | S | S | S | S | S | S | I | I |
| 24F4 | a | 36 | S | S | I | S | S | I | S | S |
| 24G1f | a | 36 | S | S | S | S | S | S | S | I |
| 29F6 | * | 43 | S | S | S | S | S | S | S | S |
| 29G6 | a | 43 | S | S | S | S | S | S | S | S |
| 29G7 | a | 43 | S | S | S | S | S | S | S | S |
| 29G8 | * | 43 | S | S | S | S | S | S | S | S |
| 29H1f | a | 43 | S | S | R | S | S | S | R | R |
a
Boldfaced isolates were used for qRT-PCR.
b
*, the isolate was not genotyped.
c
S, susceptible; I, intermediate; R, resistant. All isolates were susceptible to piperacillin, aztreonam, meropenem, netilmicin, and tobramycin.
d
Pip/Taz, piperacillin-tazobactam; Caz, ceftazidime; Cef, cefepime; Imi, imipenem; Am, amikacin; Gm, gentamicin; Nor, norfloxacin; Cip, ciprofloxacin.
e
Given as diameter for resistant isolates-diameter for susceptible isolates.
f
Isolate with a small colony diameter.