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Activity of amoxicillin in the prophylaxis of experimental endocarditis due to either of two additional vancomycin-susceptible E. faecalis isolates
| Prophylactic regimen | No. of infected rats/total no. of rats
|
|||
|---|---|---|---|---|
|
E. faecalis 309 inoculated with:
|
E. faecalis 1209 inoculated with:
|
|||
| ID90 | 10 × ID90 | ID90 | 10 × ID90 | |
| None | 5/5 | 5/5 | 5/5 | 4/4 |
| AMXa | 0/10b | 0/9b | 1/9b | 0/10b |
AMX, human simulation of single oral dose of 2 to 3 g amoxicillin.
P < 0.005 versus no treatment.
